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| The Giants' Malik Nabers (concussion) is out for Sunday's game against the Seahawks after missing practice all week. Nabers' absence naturally represents a major loss for New York's passing game and fantasy managers alike and will propel Wan'Dale Robinson and Darius Slayton into the top two receiver roles versus Seattle. Speedster Jalin Hyatt could also be due for a bump in opportunity as the No. 3 wideout after only logging three targets through the first four games. |
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| The Bills' Khalil Shakir (ankle) is out for Sunday's game against the Texans after missing practice all week. In his absence, rookie second-round pick Keon Coleman is expected to serve as the de facto No. 1 receiver for Buffalo while veterans Mack Hollins, Marques Valdez-Scantling and Curtis Samuel work behind him. Running back James Cook and tight ends Dalton Kincaid and Dawson Knox could potentially also see at least a slight bump in pass-catching opportunities. |
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| The Raiders' Davante Adams (hamstring) remains out for Sunday's game against the Broncos after missing practice all week. In Adams' second straight absence, fellow veteran Jakobi Meyers should be in store for a notable increase in opportunity, while second-year speedster Tre Tucker remains in the No. 2 role. Tight end Brock Bowers could also be a beneficiary in terms of additional targets, and Adams, who is projected to be ready to play by next week per early Sunday reports, is very likely to be traded at some point in the coming days. |
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| The Chiefs' Rashee Rice (knee) was placed on injured reserve Thursday, sidelining him for the next four games at minimum. As per Saturday night reports, Rice will meet with a renowned knee doctor and undergo an arthroscopic procedure Monday to ascertain the extent of the damage he suffered when Patrick Mahomes was knocked into him during an interception return play in a Week 4 matchup against the Chargers. There still appears to only be a minimal chance Rice can return this season, and Kansas City expects to have a definitive answer following the surgery. For the time being, speedy first-round pick Xavier Worthy, Justin Watson and JuJu Smith-Schuster are set to operate as Patrick Mahomes' top three receivers, although early Sunday reports indicate the team is also actively exploring trade opportunities for a wideout. |
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| The Packers' Romeo Doubs (personal) is out for Sunday's game against the Rams after missing practice both Thursday and Friday and then receiving a one-game suspension Saturday for conduct detrimental to the team. Doubs had finished the week listed as doubtful to play versus Los Angeles, and his absence, coupled with the expected one of Christian Watson (doubtful-ankle), will thrust Jayden Reed, Dontayvion Wicks and Bo Melton into much bigger roles in Green Bay's passing attack. |
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| The Packers' Christian Watson (ankle) is doubtful for Sunday's game against the Rams after missing practice all week. His likely absence, coupled with the confirmed one of fellow wideout Romeo Doubs (personal), will thrust Jayden Reed, Dontayvion Wicks and Bo Melton into much bigger roles in Green Bay's passing attack. |
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| The Cowboys' Brandin Cooks (knee) was placed on injured reserve Saturday, sidelining him for the next four games at minimum. In his absence, third-year wideout Jalen Tolbert is expected to move into the No. 2 role he already appeared on the verge of taking from Cooks, while speedster KaVontae Turpin steps into the No. 3 job beginning with Sunday night's game against the Steelers. |
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| The Dolphins' Odell Beckham Jr. (knee) remains on the PUP list but is listed as questionable for Sunday's game against the Patriots after practicing in full all week. If Beckham makes his season and team debut versus New England, he'll likely rotate into the No. 3 receiver role with Braxton Berrios behind starters Tyreek Hill and Jaylen Waddle. |
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| The Patriots' Kendrick Bourne (knee) remains on the PUP list but is listed as questionable for Sunday's game against the Dolphins after practicing in limited fashion all week. If the veteran does make his season debut versus Miami, he could share No. 3 receiver snaps right from the onset. |
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| The Rams' Cooper Kupp (ankle) remains out for Sunday's game against the Packers after once again missing practice all week. His absence, along with that of Puka Nacua (IR-knee), should lead to Jordan Whittington, Tutu Atwell and Demarcus Robinson once again serving as Matthew Stafford's top three wideouts versus Green Bay. Given the amount of targets vacated by the unavailability of Los Angeles' top receiver duo, running back Kyren Williams and tight end Colby Parkinson should both continue seeing additional passing game opportunities as well. |
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| The Texans' Tank Dell is off the injury report ahead of Sunday's game against the Bills after putting in a pair of limited practices and a full Friday session following a Week 4 absence due to a chest injury. In his return versus Buffalo, Dell should slot into his usual No. 3 receiver role. |
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| The Patriots' K.J. Osborn (shoulder) is questionable for Sunday's game against the Dolphins after missing practice all week. If Osborn can't suit up, the likes of Demario Douglas, Tyquan Thornton and the potentially returning Kendrick Bourne (knee) would be in line for additional opportunities. |
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| The Commanders' Noah Brown (groin) is out for Sunday's game against the Browns after missing practice Thursday and Friday following a limited Wednesday session. In his absence, Luke McCaffrey and Olamide Zaccheus are expected to serve as the No. 2 and No. 3 receivers, respectively, behind Terry McLaurin. |
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| The Texans' Robert Woods (foot) is questionable for Sunday's game against the Bills but managed to put in a limited practice Friday following an absence Thursday. If Woods can't suit up against one of his old squads, Xavier Hutchinson should fill the No. 4 receiver role. |
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| The Chiefs' Mecole Hardman (knee) is questionable for Monday night's game against the Saints but managed to finish the week with a full Friday practice after a limited session and an absence Wednesday and Thursday, respectively. If Hardman can't suit up, Skyy Moore and Xavier Worthy could potentially handle his kickoff-return and punt-return duties, respectively. |
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| The Bears' DeAndre Carter (ribs) is questionable for Sunday's game against the Panthers and finished the week with back-to-back limited practices after missing Wednesday's session. If Carter can't play, Tyler Scott would likely serve as Chicago's No. 4 receiver, while Velus Jones would be on track to take over Carter's duties as primary kickoff and punt returner. |
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| The 49ers' Chris Conley (oblique) is doubtful for Sunday's game against the Cardinals after missing practice all week. If he can't play, Jacob Cowing (questionable-shoulder) or Ronnie Bell would be in line for No. 4 receiver duties versus Arizona. |
